Galadari Ibrahim, Alkaabi Jameelah
The Faculty of Medicine and Health Sciences, United Arab Emirates University, Dermatology Department, Al-Ain Hospital, Dubai, UAE.
Skinmed. 2003 Jul-Aug;2(4):209-11. doi: 10.1111/j.1540-9740.2003.02451.x.
Axillary hyperhidrosis can be a source of social isolation and embarrassment. The available treatments are either ineffective or have intolerable side effects. The search for a simple, long-lasting, and safe treatment has led to the use of botulinum-A toxin injections in those with excessive axillary hyperhidrosis.
Fifteen patients participated in this study. All had a history of axillary hyperhidrosis of 1-6 years duration and were using different types of therapies without any benefit. Each patient was injected intradermally with 125 units of botulinum-A toxin (Dysport, Spenywood Pharmaceutical) in 5-6 points over an elliptical area on each side. Patient follow-up was performed using the iodine-starch test.
A total of 14 out of the 15 patients had complete anhidrosis 1 week after the injection. This result lasted for periods ranging from 1-6 months. No side effects were encountered.
Intradermal injection of botulinum-A toxin seems to be a safe, rapid, and effective method of treatment in axillary hyperhidrosis.
腋窝多汗症可能会导致社交孤立和尴尬。现有的治疗方法要么无效，要么有难以忍受的副作用。寻找一种简单、持久且安全的治疗方法促使人们对腋窝多汗症患者使用A型肉毒杆菌毒素注射。
15名患者参与了本研究。所有患者均有1至6年的腋窝多汗症病史，且使用过不同类型的治疗方法但均无效果。每位患者在每侧椭圆形区域的5至6个点皮内注射125单位的A型肉毒杆菌毒素（Dysport，斯宾尼伍德制药公司）。使用碘淀粉试验对患者进行随访。
15名患者中有14名在注射后1周出现完全无汗。这一结果持续了1至6个月不等。未出现副作用。
皮内注射A型肉毒杆菌毒素似乎是治疗腋窝多汗症的一种安全、快速且有效的方法。
