Wilhelm M J, Kusaka M, Pratschke J, Tilney N L
Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02150, USA.
Transplant Proc. 1998 Aug;30(5):2402-6. doi: 10.1016/s0041-1345(98)00669-1.
Chronic rejection is a process caused by an interplay of different risk factors. Early injury regardless of type, seems to be an important prognostic event. Later insults appear to contribute. As the individual components of the process are increasingly dissected and understood, means to modulate or normalize them will be forthcoming.
