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耳蜗电图信号分析:疏密短声刺激有助于梅尼埃病的诊断。

Electrocochleographic signal analysis: condensation and rarefaction click stimulation contributes to diagnosis in Menière's disorder.

作者信息

Sass K, Densert B, Magnusson M, Whitaker S

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Lund, Sweden.

出版信息

Audiology. 1998 Jul-Aug;37(4):198-206. doi: 10.3109/00206099809072974.

Abstract

Thirty patients with Menière's disorder, 11 patients with cochlear hearing loss of other aetiologies and 10 normally-hearing subjects, were investigated using transtympanic electrocochleography (TT ECochG). Alternating polarity clicks, condensation and rarefaction clicks and long tone-bursts of 1 kHz were used for stimulation. The latencies of the AP responses to click stimulation were evaluated. It was found that the latency differences between the condensation and rarefaction click-evoked responses were significantly larger in patients with Menière's disorder as compared to normal subjects and to patients with other cochlear hearing losses. It was found that the sensitivity of TT ECochG, obtained by using measurements of SP-AP ratios and the SP amplitude at 1 kHz burst stimulation, increased from 83 per cent to 87 per cent by addition of the con-rar shift measurement. The specificity of TT ECochG obtained by this combination of variables was 100 per cent in our material. The results of the study indicate that the latency shift found in responses evoked by clicks of opposite polarities in TT ECochG, can be a useful parameter in the detection of suspected endolymphatic hydrops.

摘要

对30例梅尼埃病患者、11例其他病因导致的耳蜗性听力损失患者以及10例听力正常的受试者进行了经鼓膜电耳蜗图(TT ECochG)检查。使用交替极性短声、疏密短声以及1kHz的长纯音猝发声进行刺激。评估了短声刺激诱发的动作电位(AP)反应的潜伏期。结果发现,与正常受试者以及其他耳蜗性听力损失患者相比,梅尼埃病患者中疏密短声诱发反应之间的潜伏期差异显著更大。结果发现,通过测量1kHz猝发声刺激时的总和电位-动作电位(SP-AP)比值及SP振幅获得的TT ECochG敏感性,通过增加疏密短声潜伏期偏移测量,从83%提高到了87%。在我们的研究材料中,通过这种变量组合获得的TT ECochG特异性为100%。研究结果表明,TT ECochG中相反极性短声诱发反应中发现的潜伏期偏移,可能是检测可疑内淋巴积水的一个有用参数。

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