Shearman D C, Frommer M
Fruit Fly Research Centre, School of Biological Sciences, University of Sydney, New South Wales, Australia.
Insect Mol Biol. 1998 Nov;7(4):355-66. doi: 10.1046/j.1365-2583.1998.740355.x.
A homologue of the bifunctional sex-determining gene, doublesex (dsx), has been identified in the tephritid fruit fly, Bactrocera tryoni, and has been found to be expressed in a sex-specific manner in adult flies. The male- and female-specific cDNAs are identical at their 5' ends but differ at their 3' ends and appear to be the products of alternate splicing. The level of identity of the sex-specific DSX proteins of B. tryoni with the D. melanogaster DSX proteins, across the region corresponding to the DNA binding domain and the oligomerization domains, is greater than 85%. Four sequence motifs which are ten to thirteen bases identical to the TRA/TRA-2 binding sites (thirteen-nucleotide repeat sequences) are present in the female-specific exon of the B. tryoni dsx gene.
在实蝇科果蝇昆士兰果实蝇中已鉴定出双功能性别决定基因双性基因（doublesex，dsx）的一个同源物，并且发现它在成年果蝇中以性别特异性方式表达。雄性和雌性特异性cDNA在其5'端相同，但在3'端不同，并且似乎是可变剪接的产物。在对应于DNA结合结构域和寡聚化结构域的区域中，昆士兰果实蝇的性别特异性DSX蛋白与黑腹果蝇DSX蛋白的同一性水平大于85％。昆士兰果实蝇dsx基因的雌性特异性外显子中存在四个与TRA/TRA-2结合位点（13个核苷酸重复序列）有10至13个碱基相同的序列基序。
