Ogunniyi A, Daif A K, Al-Rajeh S, AbdulJabbar M, Al-Tahan A R, Al-Bunyan M, Shamina A R
Department of Medicine, King Khalid University Hospital, Riyadh, KSA.
Acta Neurol Scand. 1998 Aug;98(2):116-20. doi: 10.1111/j.1600-0404.1998.tb01729.x.
To describe the pattern of presentation, the types of dementia and the associated conditions in Saudi patients.
Hospital-based study using DSM-IV and ICD 10 criteria for consensus diagnosis of cases from clinical information and results of investigations. Dementia subtypes were made according to NINCDS-ADRDA, NINDS-AIREN and ICD 10 criteria while CDR was used for severity grading.
A total of 77 demented patients (49 males, 28 females) were studied. The hospital frequency was 19.3/100,000 patients. The mean age at presentation was 74.6 years and age at onset was below 65 years in 17 patients. The types of dementia were: Alzheimer's disease (51.9%), vascular dementia (18.2%), mixed cases (15.6%), dementia with Parkinson's disease (7.8%) and treatable dementia (5.2%). Only 3 patients were in the severe clinical stage and infections were important causes of deterioration.
The hospital frequency appears to be low probably because of the relatively young population. The pattern of dementia with preponderance of AD is similar to that in western countries and intervention directed at the risk factors for stroke could reduce the burden of vascular dementia.
描述沙特患者的临床表现模式、痴呆类型及相关情况。
基于医院的研究，采用DSM-IV和ICD-10标准，根据临床信息和检查结果对病例进行共识诊断。痴呆亚型根据NINCDS-ADRDA、NINDS-AIREN和ICD-10标准划分，同时使用CDR进行严重程度分级。
共研究了77例痴呆患者（49例男性，28例女性）。医院发病率为19.3/100,000患者。就诊时的平均年龄为74.6岁，17例患者发病年龄低于65岁。痴呆类型包括：阿尔茨海默病（51.9%）、血管性痴呆（18.2%）、混合型（15.6%）、帕金森病痴呆（7.8%）和可治性痴呆（5.2%）。只有3例患者处于临床重度阶段，感染是病情恶化的重要原因。
医院发病率似乎较低，可能是由于人口相对年轻。以阿尔茨海默病为主的痴呆模式与西方国家相似，针对中风危险因素的干预措施可减轻血管性痴呆的负担。
