Ticho U, Cadet J C, Mahler J, Sekeles E, Bruchim A
Invest Ophthalmol Vis Sci. 1978 Jul;17(7):667-74.
The continuous argon laser beam has been applied to the trabeculum at the anterior chamber angle of one eye of nine primates. The treatment was evaluated by light and scanning electron microscopy and constant rate infusion studies at different intervals following the laser treatment. This histological studies revealed coagulative necrosis, with trabeculotomies extending into Schlemm's canal in the immediate postoperative period. However, complete closure of the laser-induced trabeculotomies by healing was observed within 1 to 3 weeks following the treatment. Outflow facility data as measured by the perfusion studies revealed somewhat increased values of the treated eye during the early 2 weeks after laser treatment. On longer follow-up, no significant outflow differences were measured between the treated and untreated eyes.
连续氩激光束已应用于9只灵长类动物一只眼睛的前房角小梁。在激光治疗后的不同时间间隔，通过光学显微镜、扫描电子显微镜和恒速灌注研究对治疗效果进行评估。这些组织学研究显示术后即刻出现凝固性坏死，小梁切开延伸至施莱姆管。然而，治疗后1至3周内观察到激光诱导的小梁切开通过愈合完全闭合。灌注研究测量的房水流畅系数数据显示，激光治疗后的最初2周内，治疗眼的值有所增加。长期随访时，治疗眼与未治疗眼之间未测量到明显的房水流畅差异。
