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黑色素瘤脾转移引起的巨脾症。

Giant splenomegaly caused by splenic metastases of melanoma.

作者信息

Kyzer S, Koren R, Klein B, Chaimoff C

机构信息

Department of Surgery A, Rabin Medical Center, Petah-Tiqva, Israel.

出版信息

Eur J Surg Oncol. 1998 Aug;24(4):336-7. doi: 10.1016/s0748-7983(98)80021-8.

DOI:10.1016/s0748-7983(98)80021-8
PMID:9725006
Abstract

Splenic metastases are rare and usually occur in the setting of widespread visceral metastases. Splenomegaly as manifestation of metastatic spread is extremely rare. A patient with melanoma and metastases to the skin and lung is described. He developed a giant painful splenomegaly. The splenectomy specimen demonstrated that the spleen was occupied by metastases from the melanoma. Metastases of melanoma may cause extreme enlargement of the spleen. If the patient's general condition is good, splenectomy is indicated in order to prevent spontaneous rupture of the spleen.

摘要

脾转移瘤罕见,通常发生于广泛的内脏转移背景下。脾肿大作为转移扩散的表现极为罕见。本文描述了一名患有皮肤和肺部转移瘤的黑色素瘤患者。他出现了巨大且疼痛的脾肿大。脾切除标本显示脾脏被黑色素瘤转移灶占据。黑色素瘤转移可能导致脾脏极度肿大。如果患者一般状况良好,为防止脾脏自发性破裂,建议行脾切除术。

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引用本文的文献

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Spontaneous splenic rupture in melanoma.黑色素瘤自发性脾破裂
Case Rep Pathol. 2014;2014:865453. doi: 10.1155/2014/865453. Epub 2014 Mar 26.
2
Solitary metachronous splenic metastasis from cutaneous melanoma.皮肤黑色素瘤的孤立性异时性脾转移
BMJ Case Rep. 2012 Oct 26;2012:bcr2012007317. doi: 10.1136/bcr-2012-007317.
3
A metachronous splenic metastases from esophageal cancer: a case report.食管癌异时性脾转移 1 例报告。
World J Surg Oncol. 2011 Sep 16;9:105. doi: 10.1186/1477-7819-9-105.