Dargent-Molina P
Institut National de la Sante et de la Recherche Médicale, Unité 149, Villejuif, France.
Curr Opin Rheumatol. 1998 Jul;10(4):357-61. doi: 10.1097/00002281-199807000-00014.
Osteoporotic fractures represent a major public health problem in Western countries, and effective, preventive interventions are urgently needed. Whether it is worthwhile to begin treatment for osteoporosis prevention in elderly women has been the subject of some controversy. Although a 65- or 70-year-old woman is entering the highest period of risk for substaining hip and other fractures, it has been suggested that starting at this age may be too late for effective prevention. However, recent research supports the view that elderly women will greatly benefit from intervention such as physical training, dietary supplementation, or even estrogen replacement therapy. Several studies also suggest that focusing on the prevention of bone loss addresses only part of the problem. Preventing falls may also contribute substantially to reducing fracture rates in the elderly.
骨质疏松性骨折是西方国家的一个主要公共卫生问题,迫切需要有效的预防性干预措施。对于老年女性是否值得开始进行骨质疏松症预防治疗一直存在一些争议。虽然65岁或70岁的女性正进入髋部及其他骨折风险最高的时期,但有人认为在这个年龄开始预防可能为时已晚,无法达到有效预防的效果。然而,最近的研究支持这样一种观点,即老年女性将从体育锻炼、膳食补充剂甚至雌激素替代疗法等干预措施中大大受益。几项研究还表明,仅关注预防骨质流失只解决了部分问题。预防跌倒也可能对降低老年人的骨折发生率有很大帮助。