Braun U, Schicker E, Hörnlimann B
Clinic of Veterinary Internal Medicine, University of Zurich, Switzerland.
Vet Rec. 1998 Jul 25;143(4):101-5. doi: 10.1136/vr.143.4.101.
The clinical findings in 50 cows with suspected and subsequently confirmed bovine spongiform encephalopathy (BSE) (group A) were compared with the clinical signs in 22 cows with suspected BSE, but with no histological evidence of the disease (group B). The chi-square test for association was used to compare the frequencies with which diagnostic signs or combinations of signs, were positive in the cows of groups A and B. When the frequency of a sign differed significantly, its sensitivity, specificity, efficiency and positive and negative predictive values were calculated. With respect to changes in behaviour the cows in group A more frequently showed increased excitability, nervous ear and eye movements, increased salivation and increased licking of the muzzle than the cows of group B. With respect to changes in sensitivity the cows in group A were more frequently hypersensitive to touch, noise and light than the cows of group B. With respect to changes in locomotion the cows in group A were more frequently ataxic than the cows in group B.
将50头疑似患有牛海绵状脑病（BSE）且随后确诊的奶牛（A组）的临床检查结果，与22头疑似患有BSE但无组织学疾病证据的奶牛（B组）的临床症状进行比较。采用卡方关联检验来比较A组和B组奶牛中诊断体征或体征组合呈阳性的频率。当某个体征的频率有显著差异时，计算其敏感性、特异性、有效性以及阳性和阴性预测值。在行为变化方面，A组奶牛比B组奶牛更频繁地表现出兴奋性增加、耳部和眼部神经运动、唾液分泌增加以及舔鼻增加。在感觉变化方面，A组奶牛比B组奶牛更频繁地对触摸、噪音和光线过敏。在运动变化方面，A组奶牛比B组奶牛更频繁地出现共济失调。
