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老年人的Zenker憩室:手术是否合理?

Zenker's diverticulum in the elderly: is operation justified?

作者信息

Crescenzo D G, Trastek V F, Allen M S, Deschamps C, Pairolero P C

机构信息

Section of General Thoracic Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

出版信息

Ann Thorac Surg. 1998 Aug;66(2):347-50. doi: 10.1016/s0003-4975(98)00502-5.

Abstract

BACKGROUND

Surgical correction of symptomatic Zenker's diverticulum is effective; however, elderly symptomatic patients may be denied surgical intervention because of perceived increased risks.

METHODS

To address this concern, we reviewed 75 patients (46 men and 29 women) found to have this condition during the past two decades.

RESULTS

Median age was 79 years (range, 75 to 91 years). Preoperative symptoms included dysphagia in 69 patients (92%), regurgitation in 61 (81%), pneumonia in 9 (12%), halitosis in 3 (4%), and weight loss in 1 (1%). Gastroesophageal reflux symptoms were noted in 27 patients (36%). Diagnosis was made by barium swallow in 63 patients, esophagoscopy in 5, and a combination of both in 7. Surgical procedures included both diverticulectomy and myotomy in 57 patients (76%), myotomy alone in 9 (12%), diverticulopexy and myotomy in 5 (7%), and diverticulectomy alone in 4 (5%). There was no in-hospital mortality. Complications occurred in 8 patients (11%) and included esophagocutaneous fistula in 4, pneumonia and urinary tract infection in 1, and wound infection, myocardial infarction, and persistent diverticulum in 1 each. Follow-up was available in 72 patients (96%) and ranged from 8 days to 17 years (median, 3.3 years). At follow-up, 64 patients (88%) were asymptomatic and 4 (6%) were improved with minimal symptoms. The remaining 4 patients (6%) have had varying degrees of dysphagia and all have been treated with periodic esophageal dilations.

CONCLUSIONS

Operation for symptomatic Zenker's diverticulum in the elderly is safe and effective and will result in resolution of symptoms and improved quality of life in most patients.

摘要

背景

有症状的Zenker憩室手术矫正有效;然而,有症状的老年患者可能因被认为风险增加而被拒绝手术干预。

方法

为解决这一问题,我们回顾了过去二十年中发现患有此病的75例患者(46例男性和29例女性)。

结果

中位年龄为79岁(范围75至91岁)。术前症状包括吞咽困难69例(92%)、反流61例(81%)、肺炎9例(12%)、口臭3例(4%)和体重减轻1例(1%)。27例患者(36%)有胃食管反流症状。63例患者通过吞钡检查确诊,5例通过食管镜检查确诊,7例通过两者结合确诊。手术方式包括憩室切除联合肌切开术57例(76%)、单纯肌切开术9例(12%)、憩室固定联合肌切开术5例(7%)和单纯憩室切除术4例(5%)。无院内死亡。8例患者(11%)出现并发症,包括食管皮肤瘘4例、肺炎和尿路感染各1例、伤口感染、心肌梗死和持续性憩室各1例。72例患者(96%)获得随访,随访时间为8天至17年(中位时间3.3年)。随访时,64例患者(88%)无症状,4例(6%)症状改善且症状轻微。其余4例患者(6%)有不同程度的吞咽困难,均接受了定期食管扩张治疗。

结论

老年有症状的Zenker憩室手术安全有效,多数患者症状可缓解,生活质量可改善。

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