Anderson R H, Ho S Y
Department of Paediatrics, Imperial College School of Medicine at National Heart and Lung Institute, London, England, UK.
Ann Thorac Surg. 1998 Aug;66(2):621-6. doi: 10.1016/s0003-4975(98)00579-7.
The surgical option of biventricular repair requires two ventricles, each fully capable of supporting the systemic or pulmonary circulation. The morphologic substrates that may preclude some hearts from biventricular repair need to be assessed.
Heart specimens were reviewed to assess the morphologic mechanisms that produce an unbalanced ventricular mass and to identify features that would, potentially, be a contraindication for biventricular repair.
Hearts with solitary and indeterminate ventricles, and hearts with essentially solitary ventricles, often have associated abnormalities of venoatrial connections and arrangement of the atrioventricular valves. In the majority of hearts with univentricular atrioventricular connections, the rudimentary and incomplete ventricle of either right or left morphology may be too small to support either the systemic or the pulmonary circulation. Straddling with overriding of the atrioventricular valve, unbalanced atrioventricular septal defect, and gross hypoplasia of one of the ventricles in hearts with biventricular connections are other mechanisms producing ventricular imbalance, which could preclude biventricular repair.
The morphologic mechanisms that result in ventricular imbalance are mainly related to the sizes and morphology of the ventricles, septal malalignment, valvar morphology, and component make-up of the ventricles. These features will influence decision-making in considering the option of biventricular repair.
双心室修复的手术选择需要两个心室,每个心室都完全有能力支持体循环或肺循环。需要评估可能使某些心脏无法进行双心室修复的形态学基础。
对心脏标本进行检查,以评估导致心室质量不平衡的形态学机制,并确定可能成为双心室修复禁忌证的特征。
单心室和不确定心室的心脏,以及基本为单心室的心脏,通常伴有腔静脉心房连接和房室瓣排列的异常。在大多数具有单心室房室连接的心脏中,右或左形态的发育不全和不完整心室可能太小,无法支持体循环或肺循环。房室瓣跨立与骑跨、不平衡的房室间隔缺损以及双心室连接心脏中一个心室的严重发育不全是导致心室不平衡的其他机制,这可能会妨碍双心室修复。
导致心室不平衡的形态学机制主要与心室的大小和形态、间隔排列不齐、瓣膜形态以及心室的组成部分有关。这些特征将影响在考虑双心室修复选择时的决策。