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运动和 tepary 豆型饮食对肥胖 Zucker 大鼠身体成分和脂肪堆积的影响。

Effect of exercise and tepary bean type diet on body composition and fat accretion in obese Zucker rats.

作者信息

Burch P E, Schemmel R A, VanHeest J C, Rodgers C D

机构信息

Department of Physical Education and Exercise Science, Michigan State University, East Lansing 48824, USA.

出版信息

Int J Obes Relat Metab Disord. 1998 Aug;22(8):751-7. doi: 10.1038/sj.ijo.0800652.

DOI:10.1038/sj.ijo.0800652
PMID:9725634
Abstract

OBJECTIVE

The effectiveness of a tepary bean high fat type diet, compared to a purified type high fat diet and exercise, on body composition in fatty Zucker rats was determined.

SUBJECTS AND DESIGN

Approximately 6-week-old female fa/fa Zucker rats were divided into four groups of 10 rats each: TE, fed the tepary bean type diet and exercised; TN, fed the tepary bean type diet and not exercised; CE, fed the purified type control diet and exercised; CN, fed the purified type control diet and not exercised. The exercise modality was treadmill running and the experiment lasted 13 weeks.

MEASUREMENTS

Body weight, cumulative food intake, body composition, weights of adipose tissues and liver, heart and gastrocnemius muscle.

RESULTS

At the end of the 13 week experiment, TE rats weighed 511 +/- 22 g and were significantly lighter than TN, 588 +/- 15 g; CE, 606 +/- 22 g; and CN, 660 +/- 27 g. All are means +/- s.e.m. The carcass of CN rats had 58, 20 and 13% more fat than TE, TN and CE rats, respectively; P < 0.01. Lean body mass was the same for all the groups of rats and ranged from means of 216-228 g. However, TE rats had significantly more fat free dry mass (FFDM) than CN rats; 68 +/- 4 vs 58 +/- 2 (means +/- s.e.m.) and tended to have more FFDM than TN and CE rats. Inguinal fat depots weighed 20-30% less in T than in C rats (diet comparisons) and also 20-30% less in E than in N rats (exercise comparisons). Perirenal/retroperitoneal fat depots weighed 25% less in TN than in CN rats and 38% less in TE than in CE rats. Exercise did not reduce perirenal/retroperitoneal fat depot weights. Parametrial fat depot weights were not influenced by diet or exercise.

CONCLUSIONS

In diets which provided 37% of the energy from fat, the incorporation of tepary beans attenuated weight gain, and subcutaneous and visceral fat gain compared to a purified type diet. Exercised rats gained less weight and subcutaneous, but not visceral fat, than non-exercised rats.

摘要

目的

确定与纯化型高脂饮食和运动相比,食用 tepary 豆高脂型饮食对肥胖 Zucker 大鼠身体成分的影响。

对象与设计

将约 6 周龄的雌性 fa/fa Zucker 大鼠分为四组,每组 10 只:TE 组,喂食 tepary 豆型饮食并进行运动;TN 组,喂食 tepary 豆型饮食但不运动;CE 组,喂食纯化型对照饮食并进行运动;CN 组,喂食纯化型对照饮食但不运动。运动方式为跑步机跑步,实验持续 13 周。

测量指标

体重、累计食物摄入量、身体成分、脂肪组织及肝脏、心脏和腓肠肌的重量。

结果

在 13 周实验结束时,TE 组大鼠体重为 511±22 克,显著轻于 TN 组(588±15 克)、CE 组(606±22 克)和 CN 组(660±27 克)。所有数据均为平均值±标准误。CN 组大鼠的胴体脂肪分别比 TE 组、TN 组和 CE 组多 58%、20%和 13%;P<0.01。所有大鼠组的去脂体重相同,范围为 216 - 228 克。然而,TE 组大鼠的无脂干质量(FFDM)显著多于 CN 组;68±4 对 58±2(平均值±标准误),且与 TN 组和 CE 组相比,TE 组大鼠的 FFDM 也有增多趋势。腹股沟脂肪库重量,T 组比 C 组(饮食比较)少 20 - 30%,E 组比 N 组(运动比较)少 20 - 30%。肾周/腹膜后脂肪库重量,TN 组比 CN 组少 25%,TE 组比 CE 组少 38%。运动并未降低肾周/腹膜后脂肪库重量。子宫旁脂肪库重量不受饮食或运动影响。

结论

在脂肪提供 37%能量的饮食中,与纯化型饮食相比,加入 tepary 豆可减轻体重增加以及皮下和内脏脂肪增加。与未运动的大鼠相比,运动的大鼠体重增加较少,皮下脂肪减少,但内脏脂肪未减少。

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