Cotrutz C, Kappas C, Theodorakos Y, Makris C, Mohan R
Medical Physics Department, Faculty of Physics, Alex. I. Cuza University, Iasi, Romania.
Comput Methods Programs Biomed. 1998 Jun;56(3):261-72. doi: 10.1016/s0169-2607(98)00029-7.
A new personal computer (PC) radiotherapy treatment planning system (RTPS) is presented. The PC-based RTPS is designed to run in the Microsoft Windows 3.11 environment (and later versions), for computers equipped with 486 or Pentium processors. The algorithm used by the new PC-based program for dose calculation belongs to the 'radiological pathlength' category and it was previously implemented on VAX 711 computers at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, NY, within EXTREP-III RTPS. The EXTREP-III program is a two-dimensional RTPS (with restricted three-dimensional capabilities), developed and used in clinical practice at MSKCC during the 1980s. The PC-based program is implemented in the Visual Basic (version 3.0) language and supports features commonly available in most photon-mode RTPSs: dose calculation for fixed, isocentric and rotational irradiation techniques, dose corrections for both internal inhomogeneities and external inhomogeneities (boluses and compensators), association of machine-specific beams with various wedges and blocks, etc. The graphic interface of the PC-based RTPS is completely new and is designed to meet the requirements of fast and accurate planning. The user interface consists of an event-oriented button-based console which allows users to perform planning and to have isodose charts overlaid on patient computed tomography images initially loaded in the program. The PC-based RTPS tests, performed in order to assess its accuracy and speed of computation, show good results. The acceptable computation times obtained, the good accuracy in dose computation and the user-friendly interface of the program are sufficient reasons to consider the PC-based RTPS a good quality-price ratio tool for radiation treatment planning in cancer therapy.
介绍了一种新型个人计算机（PC）放射治疗治疗计划系统（RTPS）。基于PC的RTPS设计用于在Microsoft Windows 3.11环境（及更高版本）中运行，适用于配备486或奔腾处理器的计算机。新的基于PC的程序用于剂量计算的算法属于“放射路径长度”类别，它先前在纽约市纪念斯隆凯特琳癌症中心（MSKCC）的VAX 711计算机上，在EXTREP-III RTPS中实现。EXTREP-III程序是一个二维RTPS（具有受限的三维功能），于20世纪80年代在MSKCC开发并用于临床实践。基于PC的程序用Visual Basic（3.0版）语言实现，并支持大多数光子模式RTPS中常见的功能：固定、等中心和旋转照射技术的剂量计算，内部不均匀性和外部不均匀性（填充物和补偿器）的剂量校正，将特定机器的射束与各种楔形物和挡块相关联等。基于PC的RTPS的图形界面是全新的，旨在满足快速准确规划的要求。用户界面由一个基于事件的按钮式控制台组成，允许用户进行规划，并将等剂量图叠加在最初加载到程序中的患者计算机断层扫描图像上。为评估其计算准确性和速度而进行的基于PC的RTPS测试显示出良好的结果。获得的可接受计算时间、剂量计算的良好准确性以及该程序用户友好的界面，足以使基于PC的RTPS成为癌症治疗中放射治疗计划的性价比良好的工具。
