Strosche H, Draese K, Zöckler C E
Leber Magen Darm. 1976;6(1):1-7.
Catheterization of the umbilical vein does allow direct access to the portal system, thus yielding information about the pathophysiology of the hepatic and splanchnic vessel system. Mesurement of the portal vein pressure in conditions of portal hypertension can be performed in the portal vein. A special, three-compartment ballon catheter is available for mesurement of intrahepatic wedge pressure. Angiography of the umbilical vein allows earlier diagnosis of metastases within the liver than other diagnostic procedures. Intraportal application of cytostatic drugs using a long term indwelling umbilical vein catheter is feasible as well. Own experiences are as yet rather limited. Three patients have been treated up to now this way; evaluation of the therapeutic results is not yet possible, because of the short duration of therapy and because of the low number of patients. The technique of umbilical vein catheterization does not seem to present any problems. Complications are rare and did not occur in our series.
脐静脉插管确实能够直接进入门静脉系统，从而获取有关肝和内脏血管系统病理生理学的信息。在门静脉高压情况下，可在门静脉中测量门静脉压力。有一种特殊的三室球囊导管可用于测量肝内楔压。与其他诊断方法相比，脐静脉造影能够更早地诊断肝内转移灶。使用长期留置的脐静脉导管在门静脉内应用细胞毒性药物也是可行的。目前我们自己的经验还相当有限。到目前为止，已有3例患者采用这种方法进行治疗；由于治疗时间短且患者数量少，目前还无法对治疗结果进行评估。脐静脉插管技术似乎不存在任何问题。并发症很少见，在我们的病例系列中未发生。
