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胃肠胰系统神经内分泌肿瘤的分子与细胞生物学方面

Molecular and cell biological aspects of neuroendocrine tumors of the gastroenteropancreatic system.

作者信息

Wiedenmann B, John M, Ahnert-Hilger G, Riecken E O

机构信息

Universitätsklinikum Charité, Humboldt-Universität Berlin, Virchow-Klinikum, Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Germany.

出版信息

J Mol Med (Berl). 1998 Aug;76(9):637-47. doi: 10.1007/s001090050261.

DOI:10.1007/s001090050261
PMID:9725766
Abstract

Neurons and neuroendocrine cells share a variety of common characteristics. Cell and molecular biological studies in recent years have improved our understanding of physiological and pathophysiological processes such as cellular growth, adhesion, and secretion of neuroendocrine cells. Here we review current findings from the area of basic research and from current clinical research relevant to improving the diagnosis and therapy of neuroendocrine tumors of the gastroenteropancreatic system.

摘要

神经元和神经内分泌细胞具有多种共同特征。近年来的细胞和分子生物学研究增进了我们对神经内分泌细胞的细胞生长、黏附及分泌等生理和病理生理过程的理解。在此,我们综述基础研究领域以及与改善胃肠胰系统神经内分泌肿瘤诊断和治疗相关的当前临床研究的现有发现。

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