Criteria for the molecular identification of the volume-sensitive outwardly rectifying Cl- channel.
作者信息
Okada Y, Oiki S, Hazama A, Morishima S
出版信息
J Gen Physiol. 1998 Sep;112(3):365-7. doi: 10.1085/jgp.112.3.365.
Abstract
摘要
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Criteria for the molecular identification of the volume-sensitive outwardly rectifying Cl- channel.容积敏感性外向整流氯离子通道的分子鉴定标准。
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Effect of cell swelling on membrane and cytoplasmic distribution of pICln.
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The GXGXG motif in the pI(Cln) protein is not important for the nucleotide sensitivity of the pI(Cln)-induced Cl- current in Xenopus oocytes.
FEBS Lett. 1998 Apr 17;426(2):171-3. doi: 10.1016/s0014-5793(98)00334-2.
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The list of potential volume-sensitive chloride currents continues to swell (and shrink).潜在的容积敏感性氯电流的清单持续增加（也在减少）。
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Molecular identity of the outwardly rectifying, swelling-activated anion channel: time to reevaluate pICln.外向整流、肿胀激活阴离子通道的分子特性：是时候重新评估pICln了。
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Protein kinase C-independent correlation between P-glycoprotein expression and volume sensitivity of Cl- channel.P-糖蛋白表达与氯离子通道容积敏感性之间不依赖蛋白激酶C的相关性。
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The chloride current induced by expression of the protein pICln in Xenopus oocytes differs from the endogenous volume-sensitive chloride current.爪蟾卵母细胞中由蛋白质pICln表达所诱导的氯电流不同于内源性容积敏感性氯电流。
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