Yoosuf H M, Rao U A, Thyagarajan S P
Department of Microbiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras.
Indian J Pathol Microbiol. 1995 Oct;38(4):349-54.
A modified Rapid urease test developed by us was evaluated as a screening test for Helicobacter pylori (H. pylori) during and endoscopy survey on patients with Acid Peptic Diseases (APD) and Non Ulcer Dyspepsia (NUD). This was compared with commercially available CLO (Campylobacter Like Organism) test, culture and histopathological examination. The modified Rapid urease test gave a sensitivity of 89.83% and a specificity of 100%, when compared to 95% sensitivity and specificity for commercially available CLO test. Our modified Rapid urease test is simple, economical and a quick test in identifying H. pylori in routine screening of patients with APD and NUD.
我们研发的改良快速尿素酶试验，作为对酸相关性疾病（APD）和非溃疡性消化不良（NUD）患者进行内镜检查期间幽门螺杆菌（H. pylori）的筛查试验进行了评估。将其与市售的CLO（类弯曲杆菌）试验、培养及组织病理学检查进行比较。与市售CLO试验95%的敏感性和特异性相比，改良快速尿素酶试验的敏感性为89.83%，特异性为100%。我们的改良快速尿素酶试验在对APD和NUD患者进行常规筛查以鉴定H. pylori时，操作简单、经济且快速。
