Shanmugam J, Naseema K, Sarada C, Rout D
Department of Microbiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Indian J Pathol Microbiol. 1995 Oct;38(4):423-6.
One hundred and twenty seven patients belonging to Neurosurgery (49), Neuromedicine (48), Cardiac medicine (30) wards and Blood donors (30) as healthy controls were investigated for the prevalence of Toxoplasmosis by means of detecting specific IgM antibody against Toxoplasma gondii (T. gondii) employing Enzyme Immuno Assay (EIA). The detection rate of specific IgM antibody against T.gondii was found to be 32.7% (16/49) among Neurosurgery patients, 20.8% (10/48) among Neuromedical patients and 20% (6/30) among Cardiac medical patients. None of the voluntary blood donors tested was found to have T. gondii IgM antibody. Maximum prevalence rate was found among female patients undergoing Neurosurgery (42.3%) followed by Neuromedical patients (40%). There is an increasing rate of prevalence of Toxoplasmosis from the lower age group upto thirty years and a declining prevalence rate among the higher age groups. The present study revealed high prevalence rate of Toxoplasmosis in Neurosurgery patients (32.7%) and in particular among female (35.2%) than male (17.8%) patients.
通过酶免疫测定法（EIA）检测抗弓形虫特异性IgM抗体，对神经外科（49例）、神经医学科（48例）、心脏内科（30例）病房的127例患者以及作为健康对照的30名献血者进行弓形虫病患病率调查。结果发现，神经外科患者中抗弓形虫特异性IgM抗体的检出率为32.7%（16/49），神经医学科患者中为20.8%（10/48），心脏内科患者中为20%（6/30）。在接受检测的自愿献血者中，未发现有弓形虫IgM抗体。接受神经外科手术的女性患者中患病率最高（42.3%），其次是神经医学科患者（40%）。从低年龄组到30岁，弓形虫病患病率呈上升趋势，而在高年龄组中患病率呈下降趋势。本研究显示，神经外科患者中弓形虫病患病率较高（32.7%），尤其是女性患者（35.2%）高于男性患者（
