Ravery V, de la Taille A, Hoffmann P, Moulinier F, Hermieu J F, Delmas V, Boccon-Gibod L
Department of Urology, CHU Bichat Claude Bernard, Paris, France.
J Endourol. 1998 Aug;12(4):335-40. doi: 10.1089/end.1998.12.335.
Balloon catheter dilatation is a low-cost alternative to open surgery in patients with ureteral strictures, leading to low morbidity and short hospitalization. The goal of this study was to evaluate the results of this technique in patients with inflammatory ureteral strictures or ureteroenteric strictures after radical cystectomy. Twenty-five ureteral strictures in 20 (15 male, 5 female) patients were consecutively treated by high-pressure balloon dilatation: 14 cases of ureteroenteric stricture (9 after ileal cutaneous diversion, and 5 after orthotopic enterocystoplasty) and 11 of ureteral stricture from various inflammatory causes (tuberculosis, iatrogenic injury, radiation therapy, parasitosis). Dilatation was performed by an antegrade (ureteroenteric strictures) or retrograde (inflammatory strictures) approach using a balloon insufflated up to 10 to 20 atm for 5 to 15 minutes. The ureter was stented for a mean time of 2.1 months (range 1-5 months). Results were evaluated clinically and radiologically (intravenous urogram or CT scan). Immediate success was assessed by intraoperative radiologic monitoring. Long-term success was defined as the absence of recurrence of the stenosis after 6 months. Nineteen procedures were successful among the 23 evaluable cases. With a mean follow-up of 16 months (range 6-39 months), the long-term success rate was 52%: 40% in ureteral strictures and 61% in ureteroenteric strictures. Five strictures secondary to cutaneous diversion and six caused by radiation therapy recurred after dilatation. After cutaneous diversion, the failure occurred mostly at the anastomosis and involved the crossed-over ureter. This study shows that high-pressure balloon dilatation of ureteral strictures has a high early success rate and a long-term success rate of 52%. It can therefore be considered as an alternative to open surgery.
对于输尿管狭窄患者,球囊导管扩张术是一种成本低廉的开放性手术替代方案,具有低发病率和短住院时间的特点。本研究的目的是评估该技术在根治性膀胱切除术后炎性输尿管狭窄或输尿管肠吻合口狭窄患者中的治疗效果。连续对20例(15例男性,5例女性)患者的25处输尿管狭窄进行了高压球囊扩张治疗:14例输尿管肠吻合口狭窄(9例为回肠皮肤造口术后,5例为原位回肠代膀胱术后),11例因各种炎性原因导致的输尿管狭窄(结核、医源性损伤、放射治疗、寄生虫感染)。采用顺行(输尿管肠吻合口狭窄)或逆行(炎性狭窄)入路进行扩张,使用充气至10至20个大气压的球囊持续5至15分钟。输尿管平均支架置入时间为2.1个月(范围1 - 5个月)。通过临床和影像学(静脉肾盂造影或CT扫描)评估结果。术中通过影像学监测评估即刻成功率。长期成功定义为6个月后狭窄无复发。在23例可评估病例中,19例手术成功。平均随访16个月(范围6 - 39个月),长期成功率为52%:输尿管狭窄患者为40%,输尿管肠吻合口狭窄患者为61%。扩张术后,5例皮肤造口术后继发的狭窄和6例放射治疗导致的狭窄复发。皮肤造口术后,失败主要发生在吻合口,累及交叉输尿管。本研究表明,输尿管狭窄的高压球囊扩张术早期成功率高,长期成功率为52%。因此,可将其视为开放性手术的替代方案。