Maksimović Z, Rsumović M, Jović V, Kosanović M, Jovanović T
Serbian Academy of Sciences and Arts, Belgrade, Yugoslavia.
J Environ Pathol Toxicol Oncol. 1998;17(3-4):221-7.
The Zlatibor district in Serbia has lower mortality rates of malignant and cardiovascular diseases (CVD) compared with other regions in Serbia. To better understand the influence of the geochemical environment, we collected and analyzed soil from various bedrocks and the grass growing on them. We also analyzed spring and stream waters, including large water supply accumulations, for major chemical elements and examined the serum of healthy adults in the large area of Zlatibor for selenium (Se) and magnesium (Mg). Our studies included villages, small towns, and the town of Uzice. Our results showed a variable Se content in the soil over different bedrocks. In general, soil in this area has a higher Se content than in other regions of Serbia. The Se content of the grass is influenced by bedrock and soil mineralogy, but mostly by soil pH and the date of collection. For example, in late summer, grass contains twice as much Se than in spring. Mg2+HCO3(-)-type waters occur in the ultramafic massif of Zlatibor in a concentration of 44 to 68 mgMg/L. The serum Se values were higher in the Zlatibor area than in other regions of Serbia (62.6 +/- 14.9 microgSe/L; n = 158). The serum Mg content (22.7 +/- 2.2 mg/L; n = 158) was in the uppermost part of the reference range. Taking into account their biological role, the Se and Mg levels in the human population in the Zlatibor area could influence the lower mortality rates of cancer and CVD in this region compared with other regions in Serbia.
与塞尔维亚其他地区相比，塞尔维亚的兹拉蒂博尔区恶性疾病和心血管疾病（CVD）的死亡率较低。为了更好地了解地球化学环境的影响，我们收集并分析了来自各种基岩的土壤以及生长在其上的草。我们还分析了泉水和溪水，包括大型供水蓄水处，以检测主要化学元素，并检测了兹拉蒂博尔大片地区健康成年人血清中的硒（Se）和镁（Mg）。我们的研究涵盖了村庄、小镇和乌日采镇。我们的结果表明，不同基岩上的土壤中硒含量各不相同。总体而言，该地区土壤中的硒含量高于塞尔维亚其他地区。草中的硒含量受基岩和土壤矿物学的影响，但主要受土壤pH值和采集日期的影响。例如，夏末时草中的硒含量是春季的两倍。Mg2+HCO3(-)型水出现在兹拉蒂博尔的超镁铁质地块中，浓度为44至68mgMg/L。兹拉蒂博尔地区的血清硒值高于塞尔维亚其他地区（62.6±14.9μgSe/L；n = 158）。血清镁含量（22.7±2.2mg/L；n = 158）处于参考范围的最高端。考虑到硒和镁的生物学作用，与塞尔维亚其他地区相比，兹拉蒂博尔地区人群中的硒和镁水平可能是该地区癌症和心血管疾病死亡率较低的原因。
