Borg M F, Olver I N, Hill M P
Royal Adelaide Hospital Cancer Centre, Royal Adelaide Hospital, Australia.
Australas Radiol. 1998 Aug;42(3):216-8. doi: 10.1111/j.1440-1673.1998.tb00496.x.
Rothmund-Thomson syndrome (RTS) is a rare disorder with a predisposition for cutaneous and non-cutaneous malignancy. It is speculated that ultraviolet (UV) sensitivity and deficient DNA repair may account for this predisposition and influence the tolerance of chemoradiotherapeutic management. A case is reported of the management of an RTS patient with squamous cell carcinoma of the tongue who demonstrated increased radiosensitivity and tissue intolerance to chemotherapy.
罗思蒙德 - 汤姆森综合征（RTS）是一种罕见的疾病，易患皮肤和非皮肤恶性肿瘤。据推测，紫外线（UV）敏感性和DNA修复缺陷可能是导致这种易感性的原因，并影响放化疗治疗的耐受性。本文报道了一例RTS患者舌鳞状细胞癌的治疗情况，该患者对放疗敏感性增加，对化疗组织耐受性差。
