Grasman J
Department of Mathematics, Agricultural University, Wageningen, The Netherlands.
Math Biosci. 1998 Aug 15;152(1):13-27. doi: 10.1016/s0025-5564(98)10020-2.
A method is presented to approximate the long-term stochastic dynamics of an epidemic modelled by state variables denoting the various classes of the population such as in SIR and SEIR model. The modelling includes epidemics in populations at different locations with migration between these populations. A logistic stochastic process for the total infectious population is formulated; it fits the long-term stochastic behaviour of the total infectious population in the full model. A good approximation is obtained if only the dynamics near the equilibria is fit.
本文提出了一种方法来近似由表示不同人群类别的状态变量所建模的流行病的长期随机动态,例如在SIR和SEIR模型中。该建模包括不同地点人群中的流行病以及这些人群之间的迁移。为总感染人群制定了一个逻辑随机过程;它符合完整模型中总感染人群的长期随机行为。如果仅拟合平衡点附近的动态,则可获得良好的近似值。