Glader B E, Buchanan G R
Pediatrics. 1976 Oct;58(4):548-55.
Serious bleeding episodes in newborn infants can usually be diagnosed following careful clinical assessment and a few simple laboratory tests. Certain conditions are found almost exclusively in "sick" infants, whereas other coagulation abnormalities occur in otherwise "healthy" neonates. Successful management of hemorrhage necessitates a correct diagnosis which thereby dictates appropirate therapy. In some cases, such as in DIC, successful outcome ultimately depends on correction of the underlying pathophysiology which triggered the coagulation disturbance.
新生儿严重出血事件通常可通过仔细的临床评估和一些简单的实验室检查来诊断。某些情况几乎仅见于“患病”婴儿,而其他凝血异常则发生在其他方面“健康”的新生儿中。成功处理出血需要正确的诊断,从而决定适当的治疗方法。在某些情况下,如在弥散性血管内凝血(DIC)中,最终的成功结果取决于引发凝血紊乱的潜在病理生理学的纠正。