Alexander F
Department of Public Health Sciences, University of Edinburgh, UK.
Radiat Environ Biophys. 1998 Jul;37(2):71-4. doi: 10.1007/s004110050096.
The EUROCLUS Project is a collaborative endeavour in which incidence data for 13 35 1 cases of childhood leukaemia (CL) diagnosed between 1980 and 1989 in 17 countries were referenced to 26 425 small geographic areas and tested for evidence of spatial clustering. A second objective of EUROCLUS was to determine whether clustering of CL was associated with community demographic features and/or proximity to putative environmental hazards. The results show statistically significant evidence of clustering, but the magnitude is small (extra-Poisson variability = 1.65% of Poisson variability). Patterns of clustering are associated with population density and other demographic features which could indicate variations in opportunity for exposure to common infections. There is no consistent evidence that clusters are associated with proximity to nuclear facilities or other putative environmental hazards.
EUROCLUS项目是一项合作研究，其中1980年至1989年期间在17个国家诊断出的13351例儿童白血病（CL）的发病率数据被参考到26425个小地理区域，并测试了空间聚集的证据。EUROCLUS的第二个目标是确定CL的聚集是否与社区人口特征和/或接近假定的环境危害有关。结果显示出具有统计学意义的聚集证据，但程度较小（超泊松变异性=泊松变异性的1.65%）。聚集模式与人口密度和其他人口特征相关，这可能表明接触常见感染的机会存在差异。没有一致的证据表明聚集与靠近核设施或其他假定的环境危害有关。
