Golda V, Hilgertová J
Institute of Experimental Neurosurgery, Hradec Králové, Czech Republic.
Physiol Res. 1997;46(6):439-42.
Glucose tolerance, insulin binding to erythrocytes, insulinaemia, plasma total cholesterol, plasma triglycerides, weight of fat pads, food consumption and body weight changes were studied in genetically hypertensive lean Koletsky rats. Long-term treatment with dopaminergic agonist terguride (0.2 mg/kg/day) normalized glucose tolerance and increased the percentage of bound insulin to erythrocytes in both sexes. Terguride decreased insulinaemia, cholesterolaemia, fat pads and body weight only in female rats. Food consumption was not influenced by terguride over the injection period.
在遗传性高血压瘦型科莱茨基大鼠中研究了葡萄糖耐量、胰岛素与红细胞的结合、胰岛素血症、血浆总胆固醇、血浆甘油三酯、脂肪垫重量、食物消耗及体重变化。用多巴胺能激动剂特古瑞得（0.2毫克/千克/天）进行长期治疗可使葡萄糖耐量正常化，并增加两性中与红细胞结合的胰岛素百分比。特古瑞得仅使雌性大鼠的胰岛素血症、胆固醇血症、脂肪垫和体重降低。在注射期间，食物消耗不受特古瑞得影响。
