Ogiso M
Department of Fixed Prosthodontics, Faculty of Dentistry, Tokyo Medical and Dental University, Japan.
J Biomed Mater Res. 1998 Fall;43(3):318-20. doi: 10.1002/(sici)1097-4636(199823)43:3<318::aid-jbm13>3.0.co;2-b.
Dense hydroxyapatite (HA) is widely believed to be unsuitable for clinical use as dental implants due to its poor mechanical properties, although it has excellent biocompatibility and is chemically stable and nonresorbable in vivo. However, the case in this article is one in which the patient's dense HA implants are still stable and in good functional condition 16.5 years after he received four pieces of a one-piece dense HA implant in both sides of his lower molar regions. Furthermore, almost no radiolucency is evident along the root portions of the implant sites in the bone. These findings imply that dense HA can be clinically useful and should be reevaluated as a dental implant material.
尽管致密羟基磷灰石（HA）具有优异的生物相容性，在体内化学性质稳定且不可吸收，但由于其机械性能较差，人们普遍认为它不适用于临床作为牙种植体。然而，本文报道了这样一个病例：患者在双侧下颌磨牙区植入了四枚一体式致密HA种植体，16.5年后这些种植体仍然稳定，功能良好。此外，在种植体植入部位的牙根周围几乎没有明显的透射区。这些发现表明，致密HA在临床上可能具有应用价值，应作为一种牙种植体材料重新进行评估。
