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肝细胞癌的病理学方面:对预后因素的批判性综述

Pathological aspects of hepatocellular carcinoma: a critical review of prognostic factors.

作者信息

Lauwers G Y, Vauthey J N

机构信息

Department of Pathology, University of Florida, Gainesville, USA.

出版信息

Hepatogastroenterology. 1998 Aug;45 Suppl 3:1197-202.

PMID:9730374
Abstract

With surgical advances the number of hepatectomy specimen has increased, leading in turn to growing information on the pathologic characteristics of hepatocellular carcinomas. Large series have delineated prognostic pathological indicators of recurrence as well as survival. The understanding by histopathologists as well as surgeons of the importance of the detailed analysis is crucial since it may dictate the therapeutic strategy. We review herein the pathological factors that are currently recorded at specialized centers and analyze their value as prognostic indicators for patients with HCC.

摘要

随着外科技术的进步,肝切除标本的数量有所增加,这反过来又带来了关于肝细胞癌病理特征的更多信息。大量研究已经明确了复发以及生存的预后病理指标。组织病理学家和外科医生对详细分析重要性的理解至关重要,因为这可能决定治疗策略。我们在此回顾目前在专业中心记录的病理因素,并分析它们作为肝癌患者预后指标的价值。

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1
Pathological aspects of hepatocellular carcinoma: a critical review of prognostic factors.肝细胞癌的病理学方面:对预后因素的批判性综述
Hepatogastroenterology. 1998 Aug;45 Suppl 3:1197-202.
2
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Ann Surg. 2009 Jan;249(1):118-23. doi: 10.1097/SLA.0b013e3181904988.
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Longterm prognosis after hepatic resection for small hepatocellular carcinoma.小肝细胞癌肝切除术后的长期预后
J Am Coll Surg. 2004 Mar;198(3):356-65. doi: 10.1016/j.jamcollsurg.2003.10.017.
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Clinicopathological features, post-surgical survival and prognostic indicators of elderly patients with hepatocellular carcinoma.老年肝细胞癌患者的临床病理特征、术后生存率及预后指标
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Operative blood loss independently predicts recurrence and survival after resection of hepatocellular carcinoma.手术失血可独立预测肝细胞癌切除术后的复发和生存情况。
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Resection of hepatocellular carcinoma: the effect of surgical margin and blood transfusion on long-term survival. Analysis of 209 consecutive patients.肝细胞癌切除术:手术切缘和输血对长期生存的影响。对209例连续患者的分析。
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Prognostic factors for hepatocellular carcinoma < or = 3 cm in diameter.直径小于或等于3厘米的肝细胞癌的预后因素
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引用本文的文献

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Elevated hepatocyte paraffin 1 and neprilysin expression in hepatocellular carcinoma are correlated with longer survival.肝细胞癌中肝细胞石蜡1和中性肽链内切酶表达升高与更长生存期相关。
Virchows Arch. 2006 Jan;448(1):35-45. doi: 10.1007/s00428-005-0081-5. Epub 2005 Oct 12.
2
Clinical significance of serum vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma.肝细胞癌患者血清血管细胞黏附分子-1水平的临床意义
World J Gastroenterol. 2004 Jul 15;10(14):2014-8. doi: 10.3748/wjg.v10.i14.2014.
3
Prognosis after hepatic resection for stage IVA hepatocellular carcinoma: a need for reclassification.
IV期A组肝细胞癌肝切除术后的预后:重新分类的必要性。
Ann Surg. 2003 Mar;237(3):376-83. doi: 10.1097/01.SLA.0000055224.68432.80.
4
Improving survival results after resection of hepatocellular carcinoma: a prospective study of 377 patients over 10 years.提高肝细胞癌切除术后的生存结果:一项对377例患者进行的为期10年的前瞻性研究。
Ann Surg. 2001 Jul;234(1):63-70. doi: 10.1097/00000658-200107000-00010.