• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Stepping back and looking forward: downregulation of G proteins as a mechanism of desensitization in tissues. Focus on "Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha".

作者信息

Jasper J R

出版信息

Am J Physiol. 1998 Sep;275(3):C634-5. doi: 10.1152/ajpcell.1998.275.3.C634.

DOI:10.1152/ajpcell.1998.275.3.C634
PMID:9730945
Abstract
摘要

相似文献

1
Stepping back and looking forward: downregulation of G proteins as a mechanism of desensitization in tissues. Focus on "Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha".回顾与展望：G蛋白下调作为组织脱敏的一种机制。聚焦于“卡巴胆碱诱导大鼠子宫肌层PLC-β信号通路脱敏：Gqα/G11α下调”
Am J Physiol. 1998 Sep;275(3):C634-5. doi: 10.1152/ajpcell.1998.275.3.C634.
2
Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha.卡巴胆碱诱导的大鼠子宫肌层磷脂酶C-β信号通路脱敏：Gqα/G11α的下调
Am J Physiol. 1998 Sep;275(3):C636-45. doi: 10.1152/ajpcell.1998.275.3.C636.
3
CCK, carbachol, and bombesin activate distinct PLC-beta isoenzymes via Gq/11 in rat pancreatic acinar membranes.
Am J Physiol. 1997 Jan;272(1 Pt 1):G135-40. doi: 10.1152/ajpgi.1997.272.1.G135.
4
Up-regulation of rat myometrial phospholipases C{beta}1 and C{beta}3 correlates with increased term sensitivity to carbachol and oxytocin.大鼠子宫肌层磷脂酶Cβ1和Cβ3的上调与足月时对卡巴胆碱和缩宫素敏感性增加相关。
J Endocrinol. 2005 Nov;187(2):197-204. doi: 10.1677/joe.1.06388.
5
Pathways used by relaxin to regulate myometrial phospholipase C.
Ann N Y Acad Sci. 2005 May;1041:300-4. doi: 10.1196/annals.1282.045.
6
Modulation of phospholipase C pathway and level of Gq alpha/G11 alpha in rat myometrium during gestation.
Am J Physiol. 1996 Sep;271(3 Pt 1):C895-904. doi: 10.1152/ajpcell.1996.271.3.C895.
7
Opioid mu, delta, and kappa receptor-induced activation of phospholipase C-beta 3 and inhibition of adenylyl cyclase is mediated by Gi2 and G(o) in smooth muscle.阿片类μ、δ和κ受体诱导的磷脂酶C-β3激活及腺苷酸环化酶抑制在平滑肌中由Gi2和G(o)介导。
Mol Pharmacol. 1996 Oct;50(4):870-7.
8
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11.老年大鼠腮腺细胞膜中M3型毒蕈碱受体和α1-肾上腺素能受体对磷脂酰肌醇-4,5-二磷酸（PIP2）水解的刺激作用减弱：Gαq/11激活缺陷
Arch Biochem Biophys. 1995 Oct 1;322(2):319-26. doi: 10.1006/abbi.1995.1470.
9
Involvement of the phospholipase C beta1 pathway in desensitization of the carbachol-activated nonselective cationic current in murine gastric myocytes.
Mol Cells. 2006 Aug 31;22(1):65-9.
10
Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes.非洲爪蟾卵母细胞中1-磷酸鞘氨醇和溶血磷脂酸之间不同的信号传导途径：非洲爪蟾卵母细胞中1-磷酸鞘氨醇受体与PLC-xβ的功能偶联
J Cell Physiol. 1998 Aug;176(2):412-23. doi: 10.1002/(SICI)1097-4652(199808)176:2<412::AID-JCP20>3.0.CO;2-3.