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[默克尔细胞癌。4例报告]

[Merkel cell carcinoma. Report of 4 cases].

作者信息

Peréz J A, Poblete M T, Castillo P, Ramírez P, de Sousa U, Pérez A

机构信息

Instituto de Cirugía, Facultad de Medicina, Universidad Austral de Chile, Chile.

出版信息

Rev Med Chil. 1998 May;126(5):553-8.

PMID:9731438
Abstract

We report four cases of Merkel cell carcinoma, a rare cutaneous neuroendocrine neoplasm with a high malignant potential. The first patient is a 90 years old male presenting with a tumor in the left superior eyelid. Surgical excision was the only treatment and seven months later, a local and regional tumoral relapse caused the death of this patient. The second patient is a 83 years old female with a tumor in her left ear. She was treated surgically and with radiotherapy, being free of disease after five years of follow up. The third patient is a 45 years old male with a tumor in the left forearm. Treatment was surgical excision of the primary tumor and axillary lymph nodes. He received post operative radiotherapy and is free of disease after three years of follow up. The last case is a 76 years old male, who was subjected only to an excisional biopsy of a lesion located in the left knee. He had a tumor relapse with inguinal and crural lymph node involvement that caused his death 12 months later.

摘要

我们报告了4例默克尔细胞癌,这是一种具有高恶性潜能的罕见皮肤神经内分泌肿瘤。首例患者为一名90岁男性,左上眼睑出现肿瘤。唯一的治疗方法是手术切除,7个月后,局部和区域肿瘤复发导致该患者死亡。第二例患者是一名83岁女性,左耳出现肿瘤。她接受了手术和放疗治疗,随访5年后无疾病。第三例患者是一名45岁男性,左前臂出现肿瘤。治疗方法是手术切除原发肿瘤和腋窝淋巴结。他接受了术后放疗,随访3年后无疾病。最后一例是一名76岁男性,仅对左膝处的病变进行了切除活检。他出现肿瘤复发并伴有腹股沟和股淋巴结受累,12个月后导致死亡。

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