Davis K L
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.
J Clin Psychiatry. 1998;59 Suppl 11:14-6.
As palliative treatments for Alzheimer's disease proliferate, the focus of therapeutics turns to drugs with the potential to alter course. Evidence is reviewed, suggesting that there is biological plausibility to utilizing anti-inflammatory agents, antioxidants, free-radical scavengers, estrogen preparations, and perhaps cholinomimetics. This range of possibilities leads to an optimistic assessment of the likelihood for altering the course or delaying the onset of Alzheimer's disease.
随着阿尔茨海默病姑息治疗方法的不断增多，治疗重点转向有可能改变病程的药物。本文对相关证据进行了综述，表明使用抗炎药、抗氧化剂、自由基清除剂、雌激素制剂以及或许还有拟胆碱药具有生物学合理性。这一系列可能性使得人们对改变阿尔茨海默病病程或延缓其发病的可能性进行了乐观评估。
