Scalvenzi M, Argenziano G, Sammarco E, Delfino M
Department of Dermatology, University of Naples Federico II, Italy.
J Eur Acad Dermatol Venereol. 1998 Jul;11(1):45-7.
The syndrome of Birt-Hogg-Dubè (BHD) is an autosomal dominant syndrome, characterized by a triad of cutaneous lesions including multiple fibrofolliculomas, trichodiscomas, and acrochordons. There are many clinical expressions, solitary and multiple forms, with or without other skin tumors. In the literature BHD syndrome has been associated with internal malignancy. We describe a patient with multiple firm, skin-colored papules in which the three types of lesion are documented. No signs of systemic disease were present.
Birt-Hogg-Dubè（BHD）综合征是一种常染色体显性综合征，其特征为三联征皮肤损害，包括多发性纤维毛囊瘤、毛发上皮瘤和皮赘。它有多种临床表现形式，有单发和多发形式，伴或不伴有其他皮肤肿瘤。在文献中，BHD综合征与内脏恶性肿瘤有关。我们描述了一位患者，其有多个质地坚实、肤色丘疹，且记录到了三种类型的损害。未发现全身性疾病的体征。
