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1980 - 1988年东柏林青少年慢性关节炎的发病率和患病率。

Incidence and prevalence of juvenile chronic arthritis in East Berlin 1980-88.

作者信息

Kiessling U, Döring E, Listing J, Meincke J, Schöntube M, Strangfeld A, Zink A

机构信息

2nd Children's Hospital, Berlin-Buch, Germany.

出版信息

J Rheumatol. 1998 Sep;25(9):1837-43.

PMID:9733469
Abstract

OBJECTIVE

To estimate the incidence and prevalence rates of juvenile chronic arthritis (JCA).

METHODS

The study population was children under 16 years of age living in the East Berlin area (part of the former German Democratic Republic). By admission order that was effective up to 1990, all children with symptoms of a rheumatic disease living in the East Berlin area had to be referred to the 2nd Children's Hospital at Berlin-Buch. This specific condition allowed us to ascertain cases from the clinical records and to calculate population rates. Based upon this data, the results of surveys with different methods of case ascertainment are compared.

RESULTS

An incidence rate of 3.5 per 100,000 and a prevalence rate of 2.0 per 10,000 children were calculated. The frequency of JCA is higher for girls, with an incidence of 4.3 per 100,000 and a prevalence of 2.3 per 10,000. The figures for boys are 2.7 per 100,000 and 1.7 per 10,000, respectively.

CONCLUSION

Because of the specific prerequisites, the population rates of prevalence and incidence that were based on clinical records can be regarded as valid in this study. Deviant results of other surveys can be explained by differences in the study design or in the diagnostic procedures used.

摘要

目的

估算青少年慢性关节炎(JCA)的发病率和患病率。

方法

研究人群为居住在东柏林地区(原德意志民主共和国的一部分)16岁以下的儿童。根据直至1990年有效的入院规定,居住在东柏林地区所有有风湿性疾病症状的儿童都必须转诊至柏林-布赫的第二儿童医院。这一特殊情况使我们能够从临床记录中确定病例并计算人群发病率。基于这些数据,比较了采用不同病例确定方法的调查结果。

结果

计算得出发病率为每10万人中有3.5例,患病率为每1万名儿童中有2.0例。JCA在女孩中的发病频率更高,发病率为每10万人中有4.3例,患病率为每1万名儿童中有2.3例。男孩的相应数字分别为每10万人中有2.7例和每1万名儿童中有1.7例。

结论

由于特定的前提条件,本研究中基于临床记录得出的患病率和发病率可视为有效。其他调查结果的偏差可通过研究设计或所用诊断程序的差异来解释。

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