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本文引用的文献

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The region of the herpes simplex virus type 1 LAT gene involved in spontaneous reactivation does not encode a functional protein.单纯疱疹病毒1型潜伏相关转录物（LAT）基因中参与自发再激活的区域不编码功能性蛋白质。
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mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.红细胞分化过程中的mRNA沉默：异质性核糖核蛋白K和异质性核糖核蛋白E1从3'端调控15-脂氧合酶的翻译。
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A segment of mRNA encoding the leader peptide of the CPA1 gene confers repression by arginine on a heterologous yeast gene transcript.编码CPA1基因前导肽的一段信使核糖核酸赋予精氨酸对异源酵母基因转录物的抑制作用。
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Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA. Influence of the structure of the 5' transcript leader on regulation by the upstream open reading frame.S-腺苷甲硫氨酸脱羧酶mRNA的细胞特异性翻译调控。5'转录本前导序列结构对上游开放阅读框调控的影响。
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Initiation codons within 5'-leaders of mRNAs as regulators of translation.作为翻译调控因子的mRNA 5'端前导序列中的起始密码子。
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人类巨细胞病毒β2.7转录本的主要开放阅读框：一种受5'区域转录后调控的蛋白质的体外表达

The major open reading frame of the beta2.7 transcript of human cytomegalovirus: in vitro expression of a protein posttranscriptionally regulated by the 5' region.

作者信息

Bergamini G, Reschke M, Battista M C, Boccuni M C, Campanini F, Ripalti A, Landini M P

机构信息

Department of Clinical and Experimental Medicine, Division of Microbiology, University of Bologna, St. Orsola Hospital, Bologna, Italy.

出版信息

J Virol. 1998 Oct;72(10):8425-9. doi: 10.1128/JVI.72.10.8425-8429.1998.

DOI:10.1128/JVI.72.10.8425-8429.1998
PMID:9733897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC110236/
Abstract

beta2.7 is the major early transcript produced during human cytomegalovirus infection. This abundantly expressed RNA is polysome associated, but no protein product has ever been detected. In this study, a stable peptide of 24 kDa was produced in vitro from the major open reading frame (ORF), TRL4. Following transient transfection, the intracellular localization was nucleolar and the expression was posttranscriptionally inhibited by the 5' sequence of the transcript, which harbors two short upstream ORFs.

摘要

β2.7是人类巨细胞病毒感染期间产生的主要早期转录本。这种大量表达的RNA与多核糖体相关，但从未检测到蛋白质产物。在本研究中，从主要开放阅读框（ORF）TRL4体外产生了一种24 kDa的稳定肽。瞬时转染后，细胞内定位在核仁，并且转录本的5'序列对表达具有转录后抑制作用，该序列含有两个短的上游开放阅读框。