Alvarez Alvarez C, Sánchez Merino J M, Busto Castañón L, Pombo Felipe F, Arnal Monreal F
Servicio de Anatomía Patológica, Hospital Juan Canalejo, La Coruña.
Actas Urol Esp. 1998 Jun;22(6):515-8.
The coincidence of an urachal adenocarcinoma with another similar tumour in other location makes necessary to separate a true primary from a metastatic adenocarcinoma. We report the case of a 66-years-old-man with an urachal mucinous adenocarcinoma and two colonic adenocarcinoma excised in the same surgical act, showing both macro and microscopic studies together with immunohistochemical techniques, that were useful to differentiate the origin of both neoplasms. Among them, the antibody to keratin 7, a cytoplasmic epithelial protein, was positive in the urachal and negative in the colonic tumour.
脐尿管腺癌与其他部位的另一种相似肿瘤同时存在，使得区分真正的原发性腺癌和转移性腺癌成为必要。我们报告了一例66岁男性病例，在同一手术中切除了脐尿管黏液腺癌和两处结肠腺癌，通过大体和显微镜检查以及免疫组化技术，有助于鉴别这两种肿瘤的起源。其中，细胞角质蛋白7抗体（一种细胞质上皮蛋白抗体）在脐尿管肿瘤中呈阳性，而在结肠肿瘤中呈阴性。
