Bogolepov N K, Fedin A I, Aristova R A, Dubrovskaia M K, Filippov M A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(8):1127-37.
The paper contains some results of a comprehensive clinical, biochemical and electrophysiological study of 120 patients with different stages of an apoplectic coma. The authors studied the gas content, acid-base balance of the cranial blood inflow and outflow in the CSF and changes of EEG and EMG. It was shown that there were different levels of CNS lesions (cortico-subcortical, meso-diencephalic, meso-pontile and bulbar level) which corresponded to certain correlations between clinical, biochemical, EEG and EMG findings. The authors describe a classificational scheme of 4 stages of an apopletic coma. Special significance in the pathogenesis of a coma along with structural lesions in the different areas of the CNS is attached to metabolic disturbances and extracerebral factors (respiratory and circulatory disorders).
本文包含对120例不同阶段中风昏迷患者进行的全面临床、生化和电生理研究的一些结果。作者研究了脑脊液中颅内血流流入和流出的气体含量、酸碱平衡以及脑电图和肌电图的变化。结果表明，存在不同程度的中枢神经系统病变（皮质-皮质下、中脑-间脑、中脑-脑桥和延髓水平），这些病变与临床、生化、脑电图和肌电图检查结果之间存在一定的相关性。作者描述了中风昏迷4个阶段的分类方案。除中枢神经系统不同区域的结构病变外，代谢紊乱和脑外因素（呼吸和循环障碍）在昏迷发病机制中具有特殊意义。
