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胃泌素瘤:定位与治疗进展

Gastrinoma: advances in localization and treatment.

作者信息

Norton J A

机构信息

University of California at San Francisco; San Francisco Veterans Affairs Medical Center, San Francisco, California, USA.

出版信息

Surg Oncol Clin N Am. 1998 Oct;7(4):845-61.

PMID:9735137
Abstract

Gastrinomas secrete gastrin and cause symptoms related to gastric acid hypersecretion that can be controlled by antisecretory medications. Primary tumors are located within the pancreas or duodenum and 60% metastasize. Liver metastases are associated with decreased survival. Localization studies especially somatostatin receptor scintigraphy are indicated to image the extent of disease. Surgery is indicated to potentially cure the patient, or control the malignant tumoral process and prolong survival.

摘要

胃泌素瘤分泌胃泌素,并引发与胃酸分泌过多相关的症状,这些症状可用抗分泌药物控制。原发性肿瘤位于胰腺或十二指肠内,60%会发生转移。肝转移与生存率降低相关。定位研究尤其是生长抑素受体闪烁扫描术,用于成像疾病的范围。手术旨在有可能治愈患者,或控制恶性肿瘤进程并延长生存期。

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Gastrinoma: advances in localization and treatment.胃泌素瘤:定位与治疗进展
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引用本文的文献

1
Gastrinoma.胃泌素瘤
Curr Treat Options Oncol. 2001 Aug;2(4):337-46. doi: 10.1007/s11864-001-0027-3.
2
Zollinger-Ellison Syndrome.佐林格-埃利森综合征
Curr Treat Options Gastroenterol. 1999 Jun;2(3):195-204. doi: 10.1007/s11938-999-0059-5.