Thompson N W
Division of Endocrine Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Surg Oncol Clin N Am. 1998 Oct;7(4):881-91.
The rationale for a multifaceted operative procedure in all MEN 1 patients with pancreaticoduodenal neuroendocrine disease who present without liver metastases is presented. The results in 36 patients with MEN 1 ZES are encouraging in that more than two-thirds are eugastrinemic and none have liver metastases after follow-up as long as 20 years.
本文提出了对所有无肝转移的1型多发性内分泌腺瘤(MEN 1)合并胰十二指肠神经内分泌疾病患者采用多方面手术程序的基本原理。36例MEN 1型胃泌素瘤患者的结果令人鼓舞,超过三分之二的患者胃泌素水平正常,且在长达20年的随访后均无肝转移。