[药物抗癫痫治疗引起的精神病理变化的临床特征]

[Clinical characteristics of psychopathologic changes induced by medicinal anti-epileptic therapy].

作者信息

Boldyrev A I, Vaĭntrub M Ia

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(8):1224-7.

Abstract

On the basis of 48 clinical observations the authors describe some psychopathological changes due to certain anticonvulsive drugs used in the treatment of epilepsy (phenobarbital with diphenin or hexamindin, phenobarbital with finlepsin and bensodiazepine). The report contains an analysis of the causes leading to complications: a relative and absolute overdosage, a negative and positive interference of drugs.

摘要

基于48例临床观察，作者描述了在癫痫治疗中使用某些抗惊厥药物（苯巴比妥与地仑丁或己酮可可碱、苯巴比妥与乙磺半胱氨酸和苯二氮卓）所导致的一些精神病理变化。该报告分析了导致并发症的原因：相对和绝对过量用药、药物的负性和正性相互作用。