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抗磷脂抗体综合征

The antiphospholipid antibody syndrome.

作者信息

Johns K R, Littlejohn G O

机构信息

Monash Medical Centre, Melbourne, Victoria.

出版信息

Aust Fam Physician. 1998 Aug;27(8):709-13.

PMID:9735489
Abstract

BACKGROUND

Recurrent miscarriages cause enormous distress and despair for sufferers. In a small number of patients this condition forms part of the antiphospholipid antibody syndrome. The anticardiolipin antibodies became quantifiable in 1983, which has meant that those suffering with this condition could be identified.

OBJECTIVE

This article reviews the current understanding of this condition and offers an approach for managing patients with various components of this syndrome.

DISCUSSION

The decision to screen for these antibodies is sometimes difficult as they can be presented in the normal population. However, by identifying the patient suffering with this condition, treatment can offered which may prevent a further miscarriage or a pregnant patient suffering a thromboembolic episode.

摘要

背景

复发性流产给患者带来巨大的痛苦和绝望。在少数患者中,这种情况是抗磷脂抗体综合征的一部分。1983年抗心磷脂抗体变得可量化,这意味着患有这种疾病的患者可以被识别出来。

目的

本文综述了对这种疾病的当前认识,并提供了一种管理患有该综合征不同组成部分患者的方法。

讨论

筛查这些抗体的决定有时很困难,因为它们也可能出现在正常人群中。然而,通过识别患有这种疾病的患者,可以提供治疗,这可能会预防进一步的流产或预防怀孕患者发生血栓栓塞事件。

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