Bakheet S M, Powe J, Ezzat A, Al Suhaibani H, Tulbah A, Rostom A
Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Clin Nucl Med. 1998 Sep;23(9):604-8. doi: 10.1097/00003072-199809000-00009.
Three patients with primary breast sarcoma showed intense F-18 FDG breast uptake on the whole-body scan. In two patients the uptake was irregular and associated with cold foci that corresponded to hypodense lesions noted on the chest CT; these represented areas of pathologically demonstrated tumor necrosis. There was also intense FDG uptake in pulmonary, axillary, and supraclavicular lymph node metastases. All lesions were confirmed by CT scan of the chest. Thus F-18 FDG positron emission tomographic scanning accurately staged the tumors in these two patients, and it documented local recurrence in the third patient. Histopathologic examination showed evidence of a high-grade sarcoma, a primary rhabdomyosarcoma, and a malignant cystosarcoma phyllodes of the breast. Similar to breast carcinoma, F-18 FDG whole-body positron emission tomographic imaging could be useful in diagnosing and staging primary breast sarcomas.
三名原发性乳腺肉瘤患者在全身扫描中显示出F-18 FDG在乳腺有强烈摄取。两名患者的摄取不规则，并伴有与胸部CT上低密度病变相对应的冷区；这些代表了病理证实的肿瘤坏死区域。肺、腋窝和锁骨上淋巴结转移灶也有强烈的FDG摄取。所有病变均经胸部CT扫描证实。因此，F-18 FDG正电子发射断层扫描准确地对这两名患者的肿瘤进行了分期，并记录了第三名患者的局部复发情况。组织病理学检查显示为高级别肉瘤、原发性横纹肌肉瘤和乳腺恶性叶状囊肉瘤。与乳腺癌相似，F-18 FDG全身正电子发射断层成像在原发性乳腺肉瘤的诊断和分期中可能有用。
