Romano J G, Rotta F T, Potter P, Rosenfeld V, Santibanez R, Rocha B, Bradley W G
Department of Neurology (D4-5), University of Miami School of Medicine, Florida 33101, USA.
Muscle Nerve. 1998 Oct;21(10):1327-30. doi: 10.1002/(sici)1097-4598(199810)21:10<1327::aid-mus14>3.0.co;2-z.
To clarify the question of whether Guillain-Barré syndrome (GBS) patients treated with intravenous immune globulin (i.v.IG) relapse at a higher frequency than those treated with plasma exchange (PE), 54 patients with GBS were studied retrospectively. A higher frequency of relapses was noted in the PE-treated patients than in those receiving i.v.IG. The presence of an associated medical condition correlated with an increased risk of relapses, while earlier onset of treatment resulted in a decrease of relapses of GBS. This study found no support for prior suggestions of increased relapses in patients with GBS treated with i.v.IG as opposed to those treated with PE.
