Hino A, Hirose T, Seki K, Uehara H, Sano N
Department of Pathology, University of Tokushima School of Medicine, Japan.
Pathol Int. 1998 Aug;48(8):649-52. doi: 10.1111/j.1440-1827.1998.tb03965.x.
A case of adenosarcoma arising from the uterine cervix of a 55-year-old female who complained of vaginal discharge is reported. A polyp, 6 x 2 x 1.5 cm in size, identified in the cervical canal was clinically diagnosed as benign cervical polyp and resected. Histologically, the polyp was composed of benign epithelial components and sarcomatous stroma wherein periglandular hypercellularity and some mitoses including atypical ones were noted. Immunohistochemically, stromal cells were positive for muscle-type actins, desmin and estrogen receptor. Adenosarcoma is a rare, biphasic tumor of the uterus and usually presents as a polypoid mass in the endometrial cavity. When they arise from the cervix, adenosarcomas may be confused with benign cervical polyps clinically and pathologically. As the former often recurs, microscopic differentiation is crucial for further treatment.
报告了一例55岁女性子宫颈腺肉瘤病例，该患者主诉有阴道分泌物。在宫颈管内发现一个大小为6×2×1.5厘米的息肉，临床诊断为良性宫颈息肉并进行了切除。组织学上，息肉由良性上皮成分和肉瘤样间质组成，其中可见腺周细胞增多以及一些有丝分裂，包括非典型有丝分裂。免疫组化显示，间质细胞肌型肌动蛋白、结蛋白和雌激素受体呈阳性。腺肉瘤是一种罕见的子宫双相肿瘤，通常表现为子宫内膜腔内的息肉样肿块。当腺肉瘤起源于宫颈时，在临床和病理上可能会与良性宫颈息肉混淆。由于前者常复发，显微镜下鉴别对于进一步治疗至关重要。
