Potts G F, Gugino L D, Leventon M E, Grimson W E, Kikinis R, Cote W, Alexander E, Anderson J E, Ettinger G J, Aglio L S, Shenton M E
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
J Clin Neurophysiol. 1998 Jul;15(4):344-50. doi: 10.1097/00004691-199807000-00006.
The perception of a visual stimulus can be inhibited by occipital transcranial magnetic stimulation. This visual suppression effect has been attributed to disruption in the cortical gray matter of primary visual cortex or in the fiber tracts leading to V1 from the thalamus. However, others have suggested that the visual suppression effect is caused by disruption in secondary visual cortex. Here the authors used a figure-eight coil, which produces a focal magnetic field, and a Quadropulse stimulator to produce visual suppression contralateral to the stimulated hemisphere in five normal volunteer subjects. The authors coregistered the stimulation sites with magnetic resonance images in these same subjects using optical digitization. The stimulation sites were mapped onto the surface of the occipital lobes in three-dimensional reconstructions of the cortical surface to show the distribution of the visual suppression effect. The results were consistent with disruption of secondary visual cortical areas.
视觉刺激的感知可被枕部经颅磁刺激所抑制。这种视觉抑制效应被认为是由于初级视觉皮层的皮质灰质或从丘脑通向V1的纤维束受到干扰所致。然而，其他人则认为视觉抑制效应是由次级视觉皮层的干扰引起的。在这里，作者使用了一个能产生聚焦磁场的8字形线圈和一个四脉冲刺激器，在五名正常志愿者受试者中产生与受刺激半球对侧的视觉抑制。作者使用光学数字化技术将这些受试者的刺激部位与磁共振图像进行了配准。在皮质表面的三维重建中，将刺激部位映射到枕叶表面，以显示视觉抑制效应的分布。结果与次级视觉皮层区域的干扰一致。
