成瘾的合理治疗。

Rational treatment of addiction.

作者信息

Terenius L

机构信息

Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.

出版信息

Curr Opin Chem Biol. 1998 Aug;2(4):541-7. doi: 10.1016/s1367-5931(98)80132-4.

DOI:10.1016/s1367-5931(98)80132-4

PMID:9736929

Abstract

Treatment of alcohol and drug addictions, which has been neglected medically for a long time, is currently sparked with optimism. Craving for alcohol can be treated with two newly registered drugs: naltrexone and acamprosate. New approaches to symptom relief during detoxification or during maintenance therapies are rationally based on experimental and clinical work. It is now clear that addictive drugs are surrogates of natural substances involved in the 'reward system'.

摘要

长期以来在医学上被忽视的酒精和药物成瘾治疗，目前正充满乐观情绪。对酒精的渴望可用两种新注册的药物治疗：纳曲酮和阿坎酸。在戒毒或维持治疗期间缓解症状的新方法合理地基于实验和临床研究。现在很清楚，成瘾性药物是参与“奖励系统”的天然物质的替代品。