Lee C W, Bociek G, Faught W
Division of Medical Oncology, University of Ottawa, Ontario, Canada.
J Pain Symptom Manage. 1998 Aug;16(2):96-101. doi: 10.1016/s0885-3924(98)00037-2.
The purpose of this study was to determine physicians' attitudes toward and preferences for palliative management of malignant ascites. A random sample of eighty physicians practicing in Canada was selected from the memberships of the Canadian Association of Medical Oncologists, the Canadian Association of Gastroenterology, the Canadian Society of Palliative Care Physicians, and the Society of Gynecologic Oncologists of Canada. Physicians were questioned on their use of different modalities in management of malignant ascites, and preferences based on attitudes toward efficacy of various treatments. Eighty surveys were mailed, with a second mailing, followed by telephone contact. The response rate was 76% (59/78), with two potential respondents deemed ineligible. Among the 44 physicians who treat malignant ascites, paracentesis is employed by 43 (98%), and felt to be effective by 39 (89%). Diuretics are used by 61% (27/44), although fewer feel diuretics are effective management (20/44, 45%). Peritoneovenous shunts, dietary measures, and other modalities are used less frequently than either paracentesis or diuretics. The most commonly used means of managing malignant ascites is paracentesis, which is also felt to be the most effective by the group surveyed. After paracentesis, diuretics and peritoneovenous shunting are used most frequently, but there is no apparent consensus as to their effectiveness. Managing malignant ascites remains problematic, and we propose further study of management strategies to clarify the role of various treatments.
本研究的目的是确定医生对恶性腹水姑息治疗的态度和偏好。从加拿大医学肿瘤学家协会、加拿大胃肠病学协会、加拿大姑息治疗医师协会和加拿大妇科肿瘤学家协会的会员中,随机抽取了80名在加拿大执业的医生。就他们在恶性腹水治疗中使用不同方法的情况,以及基于对各种治疗效果的态度的偏好对医生进行了询问。共邮寄了80份调查问卷,之后进行了第二次邮寄,并通过电话联系。回复率为76%(59/78),有两名潜在受访者被认为不符合条件。在44名治疗恶性腹水的医生中,43名(98%)采用了腹腔穿刺术,其中39名(89%)认为其有效。61%(27/44)的医生使用利尿剂,不过认为利尿剂是有效治疗方法的医生较少(20/44,45%)。腹腔静脉分流术、饮食措施和其他方法的使用频率低于腹腔穿刺术或利尿剂。治疗恶性腹水最常用的方法是腹腔穿刺术,接受调查的医生群体也认为它是最有效的。腹腔穿刺术后,利尿剂和腹腔静脉分流术的使用频率最高,但对于它们的有效性尚无明显共识。恶性腹水的治疗仍然存在问题,我们建议进一步研究治疗策略,以明确各种治疗方法的作用。