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一位患有抗Ro/SSA阳性未分化结缔组织病的母亲,其新生儿患有完全性先天性心脏传导阻滞:病例报告

Anti Ro/SSA positive undifferentiated connective tissue disease in a mother with a newborn with complete congenital heart block: a case report.

作者信息

Louthrenoo W, Boonyaratavej S, Sittiwangkul R, Sukitawut W

机构信息

Department of Medicine, Faculty of Medicine, Chiang Mai University, Thailand.

出版信息

J Med Assoc Thai. 1998 Aug;81(8):633-6.

PMID:9737117
Abstract

An association between complete congenital heart block (CCHB) and anti-Ro/SSA antibody is well recognized but has never been reported in Thailand. We report here a 37-year-old female who was admitted because of massive epistaxis secondary to immune thrombocytopenia. She had given birth to a child with CCHB 2 years previously, when she was healthy. Antinuclear antibody and anti-Ro/SSA were positive in her sera, but were negative in her son. The relationship between anti-Ro/SSA antibody and outcome of mothers with infants with CCHB is reviewed.

摘要

完全性先天性心脏传导阻滞(CCHB)与抗Ro/SSA抗体之间的关联已得到充分认识,但在泰国从未有过报道。我们在此报告一名37岁女性,因免疫性血小板减少继发大量鼻出血入院。她在两年前身体健康时生下了一名患有CCHB的孩子。她血清中的抗核抗体和抗Ro/SSA呈阳性,但她儿子的检测结果为阴性。本文对患有CCHB婴儿的母亲的抗Ro/SSA抗体与结局之间的关系进行了综述。

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