Przybyłowski J, Hajduk A, Słomba M, Obodyński K
Zakładu Medycyny Sportowej Instytutu Wychowania Fizycznego i Zdrowotnego Wyzszej Szkoły Pedagogicznej w Rzeszowie.
Wiad Lek. 1998;51(5-6):260-4.
In 18 sportsmen the platelet count, thrombin time, prothrombin time, activated partial thromboplastin time (APTT), cloting factors (F):I, VII, VIII and fibrin/fibrinogen degradation products (FDP) were measured before, immediately after progressive incremental exercise--and 30 min later. All post-exercise changes of the values were corrected for the plasma volume changes, which were calculated from hematocrit values. Platelet count, thrombin time, prothrombin time FI and FVII did not change significantly after exercise. Immediately post-exercise APTT was significantly shortened, but FVIII and FDP were significantly elevated. 30 min later FDP level normalized but FVIII and APTT changes persisted. The obtained data show that the applied physical exercise caused shift of the existing balance between coagulation and fibrinolysis towards hypercoagulability. They also confirm the necessity of taking into account post-exercise hemostasis changes in cardiological rehabilitation and endurance training in adults.
对18名运动员在进行递增性运动前、运动结束即刻以及30分钟后,测量其血小板计数、凝血酶时间、凝血酶原时间、活化部分凝血活酶时间(APTT)、凝血因子(F):I、VII、VIII以及纤维蛋白/纤维蛋白原降解产物(FDP)。运动后所有数值的变化均根据血浆容量变化进行校正,血浆容量变化由血细胞比容值计算得出。运动后血小板计数、凝血酶时间、凝血酶原时间FI和FVII无显著变化。运动结束即刻APTT显著缩短,但FVIII和FDP显著升高。30分钟后FDP水平恢复正常,但FVIII和APTT的变化依然存在。所获数据表明,进行的体育锻炼使凝血与纤溶之间现有的平衡向高凝状态转变。这些数据还证实,在成人心脏康复和耐力训练中,有必要考虑运动后止血的变化。