Weimer B, Ahrens P, Miething R, Jansen S
Abteilung für allgemeine Pädiatrie II der Universitätsklinik Frankfurt am Main.
Pneumologie. 1998 Jul;52(7):412-6.
Pulmonary hemosiderosis (PH) has been described in association with a variety of immunological and non-immunological diseases. It is characterised by iron-deficiency anaemia, hemoptysis and diffuse pulmonary infiltrates based on recurrent intraalveolar hemorrhages. We present the case of a child with pulmonary hemosiderosis and a pathological gastroesophageal reflux activity. The child suffered from recurrent anaemic episodes the age of three months (hemoglobin level up to 5.4 g/dl). The symptoms decreased after removal of the gastroesophageal reflux and accompanying steroid therapy. There has been one relapse of pulmonary hemorrhage seven months later (hemoglobin level 6.1 g/dl). Since then the patient has been in good general condition and the steroid was slowly reduced. No more anaemic episodes occurred. We discuss a possible association of pathological gastroesophageal reflux activity in pulmonary hemosiderosis.
肺含铁血黄素沉着症(PH)已被描述为与多种免疫性和非免疫性疾病相关。其特征为缺铁性贫血、咯血以及基于反复肺泡内出血的弥漫性肺部浸润。我们报告一例患有肺含铁血黄素沉着症且伴有病理性胃食管反流的儿童病例。该患儿在三个月大时出现反复贫血发作(血红蛋白水平低至5.4 g/dl)。在消除胃食管反流并进行伴随的类固醇治疗后,症状有所减轻。七个月后出现了一次肺出血复发(血红蛋白水平6.1 g/dl)。从那时起,患者的一般状况良好,类固醇药物逐渐减量。此后未再发生贫血发作。我们讨论了肺含铁血黄素沉着症中病理性胃食管反流的可能关联。