Castillo Sosa M L, Karchmer S
Bol Med Hosp Infant Mex. 1976 Sep-Oct;33(5):1123-31.
An analysis of the mechanisms of adaptation of the newborn infant, immediately after birth, is put forth. Emphasis is placed upon cardiorespiratory and metabolic homeostasis, with a description of the internal medium variations in neonates seeking spontaneous equilibrium. In Mexico City this takes 4 hours. Hypoxia is stressed as one of the most important complications of the neonatal period, requiring rapid and efficient management of the infant to avoid severe complications or even death. Intra and extracardaic hemodynamic changes, stabilization of central arterial pressure as well as sufficient cardiac output, due to proper left ventricle function are described in reference to the cardiovascular sphere. A brief mention is made of the work of both ventricles during the first days of life. The diverse hemodynamic behaviour in different vascular areas of the newborn infant might be due to the concentrations of circulating gases, pH, enzyme factors and circulating hormones.
本文提出了对新生儿出生后即刻适应机制的分析。重点在于心肺和代谢稳态，并描述了新生儿寻求自发平衡时体内介质的变化。在墨西哥城，这一过程需要4小时。强调缺氧是新生儿期最重要的并发症之一，需要对婴儿进行快速有效的处理以避免严重并发症甚至死亡。参考心血管领域，描述了心内和心外血流动力学变化、中心动脉压的稳定以及由于左心室功能正常而产生的充足心输出量。简要提及了出生后最初几天两个心室的工作情况。新生儿不同血管区域的多种血流动力学行为可能归因于循环气体浓度、pH值、酶因子和循环激素。
