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[静脉注射和口服葡萄糖:新生儿胰岛素和生长激素的产生]

[Intravenous and oral glucose: production of insulin and growth hormone in the newborn infant].

作者信息

Dorantes Alvarez L, De Los Monteros Mena A E, Matus Seueira A, Chavarría Bonequi C

出版信息

Bol Med Hosp Infant Mex. 1976 Sep-Oct;33(5):979-92.

PMID:973871
Abstract

Insulin production in response to intravenous and high and low oral glucose administration was investigated in 15 healthy fasting newborns. Results show that in spite of the fact that the highest blood glucose was obtained by the intravenous load, the highest insulin levels corresponded to the high oral glucose. The lowest blood glucose levels were found in the cases who received the low oral doses. The amounts of circulating insulin in this group were not significantly different from those in the group with I.V. glucose. In two of the groups where growth hormone was measured, the known paradoxixal increase in response to administered glucose was observed.

摘要

对15名空腹的健康新生儿进行了研究,以调查静脉注射以及口服高剂量和低剂量葡萄糖后胰岛素的分泌情况。结果显示,尽管静脉注射葡萄糖后血糖水平最高,但胰岛素水平最高的却是口服高剂量葡萄糖的情况。口服低剂量葡萄糖的新生儿血糖水平最低。该组的循环胰岛素量与静脉注射葡萄糖组相比无显著差异。在其中两组检测了生长激素的新生儿中,观察到了对葡萄糖给药的已知反常增加情况。

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